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PrestiVac

Vacuum solutions engineered for biotechnology & bioprocessing

The mostly-wet process with two dry ends — dry media powder goes in at the front, freeze-dried product comes out at the back, and containment runs both ways throughout: protecting the product from the operator, and the operator from biologically active material. The dried biologics, meanwhile, burn like any fine organic dust.

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  • HEPA Filtration

    Dried biologic fines retained

  • Containment Both Ways

    Product and operator protected

  • Built for Bioprocessing

    Media prep to fill-finish

  • Combustible-Aware

    Dried organics still burn

  • Explosion-Proof

    Manufacturing specialists

  • 1000+

    Vacuums sold worldwide

  • USA

    Designed & manufactured

  • Direct

    Buy from the manufacturer

  • NFPA 660

    ATEX / IECEx principles

Biotechnology & Bioprocessing production process explorer

Every stage. Every challenge. The right vacuum solution.

Bioprocessing runs mostly wet — but the dust concentrates at the two dry ends and demands biosafety containment everywhere. Walk the flow from raw media to finished vial.

Stage 01 — Media & buffer preparation

The front dry end — culture media, salts and buffer components are dispensed as powders, shedding the finest airborne fraction at the scale. Grounded, rated recovery starts here, because dried media is a combustible organic dust like any other.

Key challenges

A wet process with two dry ends

  • Dry Ends Of A Wet Process

    Bioprocessing is mostly liquid — but dry powder goes in at media prep and comes out at lyophilization, and that is where the dust hazard concentrates.

  • Dried Biologics Burn

    Dried proteins, sugars and culture media are combustible organic fine powders — the biology does not exempt them from dust-explosion physics.

  • Containment Runs Both Ways

    Recovery protects the product from contamination and the operator from biologically active material — one discipline serving two directions at once.

  • Lyophilized Powder Is Fine

    Freeze-dried cake fractures into a very fine, easily airborne fraction — capture at the source keeps it out of the breathing zone and off adjacent product.

  • Potent & Active Biologics

    Biologically active and potent material demands HEPA retention with sealed handling under the facility's containment protocols.

  • Buffers Aren't Biologics

    Salts and buffer components are frequently non-combustible — but the dried product they surround often is, so the product sets the recovery rule.

Dust & materials knowledge center

Know the powder. Match the recovery.

Common Biotechnology & Bioprocessing materials and recovery approaches
MaterialCombustibleRecovery approachDeep dive
Dried biologics & proteinsYes — combustible organic finesHEPA-retained recovery; sealed, containment-driven handling
Culture media powdersYesGrounded, rated recovery — the same rule any fine organic dust follows
Excipients & sugarsOften yesHEPA capture; the dried product sets the combustibility rule
Lyophilized productPer formulationHigh-frequency capture of a very fine airborne fraction
Buffers & saltsGenerally noRoutine contamination-control recovery
Potent & active biologicsContainment-criticalSealed, HEPA, protocol-driven recovery

Combustibility and severity are material- and particle-size-specific — testing and your Dust Hazard Analysis govern. Full directory: the full materials directory.

Applications in bioprocessing

Built for performance. Built for compliance.

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Representative case study

Containing Combustible Excipient Dust in a Tablet Facility

How a representative North American contract manufacturer brought lactose and blend dust under control in its compression suites — satisfying explosion safety, exposure limits and cleaning validation with one recovery architecture.

Read the full case study

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Get the right explosion proof vacuum for your application.

Tell us what you need to vacuum and where. Our technical team will recommend the PrestiVac model best suited to your material, your classification and how hard you will work it — and because we build every unit ourselves, we can modify it to fit.

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  • Legally certified explosion proof
  • Solid stainless steel construction
  • Industry-best 3-year warranty
  • Designed & manufactured in the USA
  • 200+ vacuum versions