Vacuum solutions engineered for pharmaceutical manufacturing
Sterile environments, potent powders, validated cleaning and combustible excipients — pharmaceutical housekeeping carries more simultaneous requirements than any other industry. The equipment has to satisfy all of them at once.

Stainless Construction
Wash-down friendly, hygienic surfaces
HEPA Filtration
99.99% at 0.3 µm final stage
Containment-Oriented
Capture at source, sealed disposal
Validation-Friendly
Documented, repeatable cleaning methods
Explosion-Proof
Manufacturing specialists
1000+
Vacuums sold worldwide
USA
Designed & manufactured
Direct
Buy from the manufacturer
NFPA 660
ATEX / IECEx principles
Pharmaceutical Manufacturing production process explorer
Every stage. Every challenge. The right vacuum solution.
Powder escapes at every step between the warehouse and the blister pack — each stage below is a dust generation point with its own recovery requirement.
Stage 01 — Raw material handling
Bag dumps and container transfers liberate excipient and API dust at receiving — the program's first capture point, and where sealed disposal habits are set.
Key challenges
Complex environments demand exact equipment
Cross-contamination
Product carryover between batches and lines is a quality event — recovery equipment must capture, contain and clean down.
Combustible powders
Lactose, starches, sugars, cellulose and many APIs are combustible dusts; housekeeping falls under NFPA combustible-dust requirements.
Cleaning validation
Cleaning must be consistent and demonstrable — a defined vacuum method beats variable manual technique.
Regulatory documentation
GMP expectations reach housekeeping: defined methods, schedules and records.
Downtime & efficiency
Changeover cleaning is on the critical path; faster, single-pass recovery shortens it.
Worker exposure
Potent compounds drive exposure limits far below nuisance-dust levels — capture at the source with HEPA-retained exhaust.
Dust & materials knowledge center
Understand the dusts. Choose the right recovery.
| Material | Combustible | Recovery approach | Deep dive |
|---|---|---|---|
| Lactose | Yes | HEPA-filtered recovery; explosion-proof where quantity and area classification require | |
| API powders | Commonly — treat as combustible until tested | Containment-oriented HEPA recovery sized to the compound's exposure limit | |
| Sugar | Yes | Explosion-proof recovery; a classic combustible dust | |
| Starch | Yes | Explosion-proof recovery with grounded accessories | |
| Microcrystalline cellulose | Yes | HEPA-filtered recovery; grounded path for fine fractions | |
| Talc | No — inert mineral | HEPA-filtered recovery for hygiene and exposure control |
Combustibility and severity are material- and particle-size-specific — testing and your Dust Hazard Analysis govern. Full directory: pharmaceutical dusts.
Applications in pharma
- API manufacturing
- Tablet production
- Capsule production
- Powder transfer
- Powder blending
- Granulation
- Fluid bed drying
- Packaging
- Cleanrooms
- View all
Built for performance. Built for compliance.
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HEPA Vacuums
99.99% filtration for fine and hazardous dust
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Explosion Proof Vacuums
Grounded, bonded recovery for combustible dust
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Central Vacuum Systems
Facility-wide housekeeping from fixed drops
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Accessories
Grounded hoses, tools and filters
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Representative case study
Containing Combustible Excipient Dust in a Tablet Facility
How a representative North American contract manufacturer brought lactose and blend dust under control in its compression suites — satisfying explosion safety, exposure limits and cleaning validation with one recovery architecture.
Read the full case studyTalk to the manufacturer
Get the right explosion proof vacuum for your application.
Tell us what you need to vacuum and where. Our technical team will recommend the PrestiVac model best suited to your material, your classification and how hard you will work it — and because we build every unit ourselves, we can modify it to fit.
- Legally certified explosion proof
- Solid stainless steel construction
- Industry-best 3-year warranty
- Designed & manufactured in the USA
- 200+ vacuum versions
